Revitalizing your body's Defense to Combat Cancers
Comediennes for instance Gilda Radner in addition to Madeline Kahn,
Oscar-winning actresses such as Loretta Fresh in addition to Exotic
Dennis, singers Laura Nyro in addition to Dinah Shore, actor or actress
Pierce Brosnan's wife Cassandra Harris, celebrity Jessica Tandy, ex -
Connecticut governor Ella Grasso, in addition to Martin Luther King's
wife Coretta Scott King most passed on regarding ovarian melanoma. It
isn't really just celebrities, politicians or perhaps celebrities,
who're upset using ovarian melanoma. 1 atlanta divorce attorneys
fityfive You. Utes. females is in chance for ovarian melanoma. The
particular American Most cancers Society rates regarding 22, 000 fresh
conditions regarding ovarian melanoma are going to be determined. A lot
more than 07, 000 females will probably die since the signs can be
refined, in addition to the girl doctor didn't realize this signs soon
enough. It does not take top reason for death coming from gynecologic
malignancies, and the 5th top reason for melanoma deaths involving
females.
Silent in addition to unknown, this kind of melanoma typically distributes outside of this ovary or perhaps ovaries in the abdominal hole, or perhaps by the last level, in to other entire body bodily organs such as the hard working liver or perhaps bronchi. Loved ones physicians typically are not able to properly spot "The Silent Killer" till it really is as well overdue. Previous August, College regarding Ca Davis analysts documented forty five percent regarding females told his or her physicians regarding his or her signs for as long as 1 year ahead of we were holding properly determined. A Uk study observed 70 percent regarding loved ones physicians thought signs are merely current through the state-of-the-art phases with the melanoma. Through the moment females tend to be determined for ovarian melanoma, forty five to be able to 50 percent with the people will be in this state-of-the-art level, exactly where there may be very little expect survival.
Lower than one-half the ladies informed they have ovarian melanoma will probably live five decades. Concerning 10 to be able to 15 percent live outside of five decades right after his or her medical diagnosis. Their particular possibilities are already limited, primarily earmarked to be able to versions regarding chemotherapy drugs or maybe a fresh solution to shipping and delivery this substance. The public is usually unacquainted with the side consequences ovarian melanoma people undergo while in chemotherapy. With middle of the 03, this You. Utes. Meal in addition to Medicine Administration criticized this security account regarding Eli Lilly's Gemzar for ovarian melanoma people, indicating the 2. 8 months greater survival observed in research regarding people having this substance has not been adequate to be able to balance out this treatment's greater toxicity including anemia, neutropenia (a our blood disorder) in addition to thrombocytopenia (reduced platelets within the blood).
At this time utilised first-line remedies for ovarian melanoma people contain Cisplatin, using related negative effects for instance sensation problems, kidney and/or ear damage, Carboplatin (side consequences: sensation problems damage within the hands and/or lower limbs, joint pain, and/or thrombocytopenia), Paclitaxel (neurotoxicity), or perhaps Melphalan, using negative effects as well as irreversible cuboid marrow malfunction, cuboid marrow suppression).
A lady upset using ovarian melanoma faces first surgical treatment, subsequently chemotherapy. Latest popular media heralding a new progress within dealing with ovarian melanoma, intra-abdominal or perhaps intraperitoneal chemotherapy, is of which: far more chemotherapy. The particular "belly bath tub, inches as it is nicknamed through a number of television reporters, it is very praised since the remedy can certainly prolong living through regarding 07 months more than "regular" chemotherapy. The effects ended up first released within the prestigious Completely new The uk Newspaper regarding Medicine within 12 2005. Most media studies never talk about of which just forty five percent with the females dealt with with the tummy bath tub could actually complete most 6 menstrual cycles. Exactly why? The treatment is based after infusions regarding Paclitaxel in addition to Cisplatin (see negative effects in the previous paragraph). In line with Dr. Robert Edwards, exploration home with the Magee-Women's Gynecologic Most cancers within Pittsburgh, "Many females don't really feel sufficiently to operate all through this intra-abdominal (therapy). inches Many people, for instance Cindy Pakalnis regarding Marshall (Pennsylvania) have got referred to as this remedies "grueling. inches
The particular unsolved problem regarding chemotherapy is the cut of this "quality regarding living. inches Although some living file format may be established, this patient's living deteriorates. Many people battle with balancing losing within total well being with the rigors with the treatment. Analysts tend to be positively seeking fresh information that will a number of morning provide fresh expect this ovarian melanoma patient. A College regarding Minnesota study provides proposed the usage of thalidomide, which will supply in conjunction with chemotherapy, as a prospective way of increasing it is likely that remission. Minnesota melanoma analyst Dr. Levi Downs explained, "It inhibits this tumour coming from creating fresh leading to tinnitus. Devoid of fresh leading to tinnitus, this tumour are unable to completely give food to fresh tissue, hence the melanoma are unable to mature. inches His or her randomized trial seemed to be little using just 65 people (only 28 got thalidomide), and even more tests will certainly be expected.
Completely new A solution to Ovarian Most cancers Affected individuals?
1 encouraging engineering that is developed over the past several years is actually OvaRex® MAb. It absolutely was produced by ViRexx Medical Corp., an Edmonton-based organization, which often trading around the American Stock exchange (ticker token: REX) in addition to around the Toronto Stock exchange (ticker token: VIR). Currently certified to be able to Unither Prescription drugs, the entirely possessed subsidiary regarding Usa Therapeutics (NASDAQ: UTHR), OvaRex® MAb is undergoing a couple the exact same Step III trials from regarding 64 exploration centers across the united states. 1 trial provides finished application, as outlined by the middle of the 12 media launch released through ViRexx Medical Corp.
All of us chatted using ViRexx Medical Corp's Ceo, Dr. Tyrrell who was simply this Dean with the Teachers regarding Medicine in addition to Dental care for the College regarding Alberta and the Home with the Glaxo History Exploration Start. "OvaRex® MAb is actually our own guide applicant for the treating ovarian melanoma, and is particularly an 4 infusion of your monoclonal antibody, inches this individual claimed. Monoclonal antibodies are a fresh variety of biotech drugs which have been very specific; that is, every antibody binds to be able to merely one specific antigen. In the matter of OvaRex® MAb, it is a monoclonal antibody of which binds especially towards the CA-125 antigen. Dr. Tyrrell added in, "The remedy won't carry long, and is particularly granted just about every month for the first 3 needles, and then after just about every a couple of months before patient relapses".
Dr. Tyrrell mentioned the current Step III research, "The trials tend to be constant. All the people have got effectively finished his or her surgical treatment in addition to front-line chemotherapy and are at this point within cures call up this 'watchful waiting' interval. It's in this particular stage we handle this people using OvaRex® MAb with the hope regarding increasing some time to be able to illness relapse. inches They explained this repeat pace is incredibly loaded with this level III and 4 overdue varieties of ovarian melanoma, which has a time for it to relapse of around 10. four months. Affected individuals with ventured into OvaRex wish to wait of which relapse. Tyrrell noted, "In the initial study, the common time for it to relapse seemed to be delayed through regarding 15 months. When we can achieve that distinction or perhaps better with the current economic Step III trials, it will be a major enhance for the treating ovarian melanoma. inches They desires an analysis with the recent OvaRex® MAb research for being finished by the subsequent or perhaps 3 rd one fourth regarding 2007.
Why is OvaRex® MAb distinctive from other immunotherapeutic remedies is actually, rather then approaching the male body's cancer tissue directly, this monoclonal antibody locates this cancer antigen within blood flow. Many imagine it assists retrain the male body's body's defence mechanism to be able to combat this ovarian melanoma tissue. The particular process of which reportedly provides made OvaRex® MAb efficient is actually just how this signals our bodies to acknowledge in addition to combat this CA-125.
ViRexx provides addressed this "tolerance problem" the entire body suffers when it's got turn into induced which has a malignant tumour. The particular theory at the rear of this ceiling matter is actually which the entire body does not realize this CA-125 antigen as hazardous. Launching the overseas antibody, in cases like this this mouse button antibody against CA125, the male body's defense techniques tend to be woke up towards the ovarian melanoma tissue. This commences the sequence problem notifying this body's defence mechanism to battle this invading antibody CA125 sophisticated. The male body's defense techniques tend to be reprogrammed to be able to episode this CA-125 antigen in addition to find to be able to eliminate this. As well as of which break down occurs this attempt with the the immune system reaction to get rid of the cancer tissue through the entire body.
As with numerous revolutionary medical strides, serendipity is actually what exactly sits at the rear of this OvaRex® MAb history. Together engineering was being developed, another : this murine monoclonal antibody remedy for ovarian melanoma : happened by mistake. All of us talked to be able to their designer, Dr. Antoine Noujaim, about the biotech drug's roots. "It emerged out of your imaging engineering, inches this Teacher Emeritus with the College regarding Alberta explained. Inside the earlier 1980s, biotech firms, for instance Immunomedics in addition to Cytomedics ended up studying tumors in addition to making use of antibodies to be able to graphic this tumors so they could be evaluated in the melanoma patient's entire body. "I worked with Dr. Paul Longenecker in addition to most of us founded a corporation referred to as Biomira (Toronto: BRA) within 1984, inches Dr. Noujaim recalled. "We received quite a few locates and then required to help make specific antibodies. inches Section of the work seemed to be to selected types of cancer, for instance prostate, breast in addition to ovarian melanoma.
"We developed antibodies against the mucin, which often is really a glycopeptide, inches explained Dr. Noujaim. "It's the peptide with a lots of sugars onto it within this ascitis water coming from ovarian melanoma people. inches Which is just how Dr. Noujaim in addition to the crew developed additionally, firm abs earlier antibody that is at this point used by OvaRex® MAb. "We routed some antibodies to be able to Teacher Richard Baum within Malaysia for imaging regarding ovarian melanoma people, inches Noujaim thought of. "Dr. Baum called again, later, in addition to told me, 'The people My partner and i seemed to be imaging here received state-of-the-art ovarian melanoma in addition to a number of them seem to have done rather effectively right after most of us presented them several photographs (of this B43. 13 antibody, this professional medical identify for OvaRex® MAb) to be able to graphic this tumour. ' My partner and i believed this individual seemed to be kidding when camping. inches
This is serendipity at the job as Dr. Noujaim told people. "Richard seemed to be imaging people that have been within the last phases with the illness, inches this individual pointed out. Monoclonal antibodies can be utilized as analysis agencies within oncology, when they tend to be radiolabeled which has a gun which can be imaged through additional detectors. "These people received probably around a half dozen months to call home. Abruptly, 1 year later on and they're nevertheless all around. inches Baum urged Noujaim to investigate this kind of additional. Dr. Noujaim recalls your pet indicating, "Something is happening here. We've observed a huge selection of people, although nothing like this kind of. inches From this confidence, Noujaim commenced making this potential process regarding just how this kind of monoclonal antibody works. His or her well-defined head chased this baffling issues brought up through Dr. Baum's findings.
At this point regarding the memories, Noujaim received fired up, "Through pure serendipity, most of us ended up making use of murine antibodies, certainly not humanized antibodies. All of us ended up making use of overseas antibodies, a bit of overseas antibodies. inches Precisely how on the globe did Noujaim recognize to make use of murine (mouse) antibodies? "Because that had been the way to try and do this imaging back then, inches this individual sent a reply. "Before you come up with a chimeric (something derived from a couple different pet species) antibody, you choose the murine one particular. When that one functions, you humanize this antibody. inches From this exploration, Noujaim set up a corporation referred to as AltaRex, which was used community within 1995. "We brought up regarding $30 trillion in addition to expanded this program. inches
The particular significant work in order to develop this antibodies commenced within 1996. Having performed trials within Nova scotia in addition to European countries, it had been the "massive undertaking" Noujaim told people. "We received above 500 people being injected with the murine monoclonal antibody. inches They extrapolated outside of OvaRex® MAb, indicating, "We've established absolutely this process regarding actions about this, just how this functions. It's so exclusive it may connect with every one of the other antibodies we have now. inches Noujaim considers it could possibly connect with breast, ovarian, prostate in addition to pancreatic melanoma. In fact, BrevaRex® MAb for breast melanoma in addition to a number of myeloma people provides finished Step 1 trials, in addition to ProstaRex® MAb for prostate melanoma people is in this pre-clinical level.
"Our research thus far may perhaps demonstrate of which vaccines may perhaps slow this progress with the tumour using an excellent security account, inches came to the conclusion Dr. Noujaim. He then added in something which contains examining additional, "There is the very initial (ovarian cancer) patient who was simply being injected within 1987. She actually is within Malaysia, in addition to as outlined by Dr. Baum the lady seemed to be nevertheless well a year ago. inches That's just about 9 decades later on! "It's the issue regarding good take great pride in to me of which many people whom acquired OvaRex® MAb tend to be well these days, inches this individual claimed.
While the organization provides certified, below the movie stars agreement, this OvaRex® MAb engineering to be able to Usa Therapeutics, as a result of of which businesses subsidiary, Unither Prescription drugs, ViRexx provides kept protection under the law to many new member nations regarding the european union in addition to selected other countries. Important types contain Portugal, england and the Benelux countries. ViRexx in addition has founded organizing interactions using Dompé Farmaceutici, Medison Pharma, Ltd. in addition to Genesis Pharma Utes. A. for many European in addition to Middle-East Nations around the world.
COPYRIGHT LAWS © 2007 through StockInterview, Inc. JUST ABOUT ALL RIGHTS APPROPRIATED.
Post Source: http: //EzineArticles. com/168741
Lower than one-half the ladies informed they have ovarian melanoma will probably live five decades. Concerning 10 to be able to 15 percent live outside of five decades right after his or her medical diagnosis. Their particular possibilities are already limited, primarily earmarked to be able to versions regarding chemotherapy drugs or maybe a fresh solution to shipping and delivery this substance. The public is usually unacquainted with the side consequences ovarian melanoma people undergo while in chemotherapy. With middle of the 03, this You. Utes. Meal in addition to Medicine Administration criticized this security account regarding Eli Lilly's Gemzar for ovarian melanoma people, indicating the 2. 8 months greater survival observed in research regarding people having this substance has not been adequate to be able to balance out this treatment's greater toxicity including anemia, neutropenia (a our blood disorder) in addition to thrombocytopenia (reduced platelets within the blood).
At this time utilised first-line remedies for ovarian melanoma people contain Cisplatin, using related negative effects for instance sensation problems, kidney and/or ear damage, Carboplatin (side consequences: sensation problems damage within the hands and/or lower limbs, joint pain, and/or thrombocytopenia), Paclitaxel (neurotoxicity), or perhaps Melphalan, using negative effects as well as irreversible cuboid marrow malfunction, cuboid marrow suppression).
A lady upset using ovarian melanoma faces first surgical treatment, subsequently chemotherapy. Latest popular media heralding a new progress within dealing with ovarian melanoma, intra-abdominal or perhaps intraperitoneal chemotherapy, is of which: far more chemotherapy. The particular "belly bath tub, inches as it is nicknamed through a number of television reporters, it is very praised since the remedy can certainly prolong living through regarding 07 months more than "regular" chemotherapy. The effects ended up first released within the prestigious Completely new The uk Newspaper regarding Medicine within 12 2005. Most media studies never talk about of which just forty five percent with the females dealt with with the tummy bath tub could actually complete most 6 menstrual cycles. Exactly why? The treatment is based after infusions regarding Paclitaxel in addition to Cisplatin (see negative effects in the previous paragraph). In line with Dr. Robert Edwards, exploration home with the Magee-Women's Gynecologic Most cancers within Pittsburgh, "Many females don't really feel sufficiently to operate all through this intra-abdominal (therapy). inches Many people, for instance Cindy Pakalnis regarding Marshall (Pennsylvania) have got referred to as this remedies "grueling. inches
The particular unsolved problem regarding chemotherapy is the cut of this "quality regarding living. inches Although some living file format may be established, this patient's living deteriorates. Many people battle with balancing losing within total well being with the rigors with the treatment. Analysts tend to be positively seeking fresh information that will a number of morning provide fresh expect this ovarian melanoma patient. A College regarding Minnesota study provides proposed the usage of thalidomide, which will supply in conjunction with chemotherapy, as a prospective way of increasing it is likely that remission. Minnesota melanoma analyst Dr. Levi Downs explained, "It inhibits this tumour coming from creating fresh leading to tinnitus. Devoid of fresh leading to tinnitus, this tumour are unable to completely give food to fresh tissue, hence the melanoma are unable to mature. inches His or her randomized trial seemed to be little using just 65 people (only 28 got thalidomide), and even more tests will certainly be expected.
Completely new A solution to Ovarian Most cancers Affected individuals?
1 encouraging engineering that is developed over the past several years is actually OvaRex® MAb. It absolutely was produced by ViRexx Medical Corp., an Edmonton-based organization, which often trading around the American Stock exchange (ticker token: REX) in addition to around the Toronto Stock exchange (ticker token: VIR). Currently certified to be able to Unither Prescription drugs, the entirely possessed subsidiary regarding Usa Therapeutics (NASDAQ: UTHR), OvaRex® MAb is undergoing a couple the exact same Step III trials from regarding 64 exploration centers across the united states. 1 trial provides finished application, as outlined by the middle of the 12 media launch released through ViRexx Medical Corp.
All of us chatted using ViRexx Medical Corp's Ceo, Dr. Tyrrell who was simply this Dean with the Teachers regarding Medicine in addition to Dental care for the College regarding Alberta and the Home with the Glaxo History Exploration Start. "OvaRex® MAb is actually our own guide applicant for the treating ovarian melanoma, and is particularly an 4 infusion of your monoclonal antibody, inches this individual claimed. Monoclonal antibodies are a fresh variety of biotech drugs which have been very specific; that is, every antibody binds to be able to merely one specific antigen. In the matter of OvaRex® MAb, it is a monoclonal antibody of which binds especially towards the CA-125 antigen. Dr. Tyrrell added in, "The remedy won't carry long, and is particularly granted just about every month for the first 3 needles, and then after just about every a couple of months before patient relapses".
Dr. Tyrrell mentioned the current Step III research, "The trials tend to be constant. All the people have got effectively finished his or her surgical treatment in addition to front-line chemotherapy and are at this point within cures call up this 'watchful waiting' interval. It's in this particular stage we handle this people using OvaRex® MAb with the hope regarding increasing some time to be able to illness relapse. inches They explained this repeat pace is incredibly loaded with this level III and 4 overdue varieties of ovarian melanoma, which has a time for it to relapse of around 10. four months. Affected individuals with ventured into OvaRex wish to wait of which relapse. Tyrrell noted, "In the initial study, the common time for it to relapse seemed to be delayed through regarding 15 months. When we can achieve that distinction or perhaps better with the current economic Step III trials, it will be a major enhance for the treating ovarian melanoma. inches They desires an analysis with the recent OvaRex® MAb research for being finished by the subsequent or perhaps 3 rd one fourth regarding 2007.
Why is OvaRex® MAb distinctive from other immunotherapeutic remedies is actually, rather then approaching the male body's cancer tissue directly, this monoclonal antibody locates this cancer antigen within blood flow. Many imagine it assists retrain the male body's body's defence mechanism to be able to combat this ovarian melanoma tissue. The particular process of which reportedly provides made OvaRex® MAb efficient is actually just how this signals our bodies to acknowledge in addition to combat this CA-125.
ViRexx provides addressed this "tolerance problem" the entire body suffers when it's got turn into induced which has a malignant tumour. The particular theory at the rear of this ceiling matter is actually which the entire body does not realize this CA-125 antigen as hazardous. Launching the overseas antibody, in cases like this this mouse button antibody against CA125, the male body's defense techniques tend to be woke up towards the ovarian melanoma tissue. This commences the sequence problem notifying this body's defence mechanism to battle this invading antibody CA125 sophisticated. The male body's defense techniques tend to be reprogrammed to be able to episode this CA-125 antigen in addition to find to be able to eliminate this. As well as of which break down occurs this attempt with the the immune system reaction to get rid of the cancer tissue through the entire body.
As with numerous revolutionary medical strides, serendipity is actually what exactly sits at the rear of this OvaRex® MAb history. Together engineering was being developed, another : this murine monoclonal antibody remedy for ovarian melanoma : happened by mistake. All of us talked to be able to their designer, Dr. Antoine Noujaim, about the biotech drug's roots. "It emerged out of your imaging engineering, inches this Teacher Emeritus with the College regarding Alberta explained. Inside the earlier 1980s, biotech firms, for instance Immunomedics in addition to Cytomedics ended up studying tumors in addition to making use of antibodies to be able to graphic this tumors so they could be evaluated in the melanoma patient's entire body. "I worked with Dr. Paul Longenecker in addition to most of us founded a corporation referred to as Biomira (Toronto: BRA) within 1984, inches Dr. Noujaim recalled. "We received quite a few locates and then required to help make specific antibodies. inches Section of the work seemed to be to selected types of cancer, for instance prostate, breast in addition to ovarian melanoma.
"We developed antibodies against the mucin, which often is really a glycopeptide, inches explained Dr. Noujaim. "It's the peptide with a lots of sugars onto it within this ascitis water coming from ovarian melanoma people. inches Which is just how Dr. Noujaim in addition to the crew developed additionally, firm abs earlier antibody that is at this point used by OvaRex® MAb. "We routed some antibodies to be able to Teacher Richard Baum within Malaysia for imaging regarding ovarian melanoma people, inches Noujaim thought of. "Dr. Baum called again, later, in addition to told me, 'The people My partner and i seemed to be imaging here received state-of-the-art ovarian melanoma in addition to a number of them seem to have done rather effectively right after most of us presented them several photographs (of this B43. 13 antibody, this professional medical identify for OvaRex® MAb) to be able to graphic this tumour. ' My partner and i believed this individual seemed to be kidding when camping. inches
This is serendipity at the job as Dr. Noujaim told people. "Richard seemed to be imaging people that have been within the last phases with the illness, inches this individual pointed out. Monoclonal antibodies can be utilized as analysis agencies within oncology, when they tend to be radiolabeled which has a gun which can be imaged through additional detectors. "These people received probably around a half dozen months to call home. Abruptly, 1 year later on and they're nevertheless all around. inches Baum urged Noujaim to investigate this kind of additional. Dr. Noujaim recalls your pet indicating, "Something is happening here. We've observed a huge selection of people, although nothing like this kind of. inches From this confidence, Noujaim commenced making this potential process regarding just how this kind of monoclonal antibody works. His or her well-defined head chased this baffling issues brought up through Dr. Baum's findings.
At this point regarding the memories, Noujaim received fired up, "Through pure serendipity, most of us ended up making use of murine antibodies, certainly not humanized antibodies. All of us ended up making use of overseas antibodies, a bit of overseas antibodies. inches Precisely how on the globe did Noujaim recognize to make use of murine (mouse) antibodies? "Because that had been the way to try and do this imaging back then, inches this individual sent a reply. "Before you come up with a chimeric (something derived from a couple different pet species) antibody, you choose the murine one particular. When that one functions, you humanize this antibody. inches From this exploration, Noujaim set up a corporation referred to as AltaRex, which was used community within 1995. "We brought up regarding $30 trillion in addition to expanded this program. inches
The particular significant work in order to develop this antibodies commenced within 1996. Having performed trials within Nova scotia in addition to European countries, it had been the "massive undertaking" Noujaim told people. "We received above 500 people being injected with the murine monoclonal antibody. inches They extrapolated outside of OvaRex® MAb, indicating, "We've established absolutely this process regarding actions about this, just how this functions. It's so exclusive it may connect with every one of the other antibodies we have now. inches Noujaim considers it could possibly connect with breast, ovarian, prostate in addition to pancreatic melanoma. In fact, BrevaRex® MAb for breast melanoma in addition to a number of myeloma people provides finished Step 1 trials, in addition to ProstaRex® MAb for prostate melanoma people is in this pre-clinical level.
"Our research thus far may perhaps demonstrate of which vaccines may perhaps slow this progress with the tumour using an excellent security account, inches came to the conclusion Dr. Noujaim. He then added in something which contains examining additional, "There is the very initial (ovarian cancer) patient who was simply being injected within 1987. She actually is within Malaysia, in addition to as outlined by Dr. Baum the lady seemed to be nevertheless well a year ago. inches That's just about 9 decades later on! "It's the issue regarding good take great pride in to me of which many people whom acquired OvaRex® MAb tend to be well these days, inches this individual claimed.
While the organization provides certified, below the movie stars agreement, this OvaRex® MAb engineering to be able to Usa Therapeutics, as a result of of which businesses subsidiary, Unither Prescription drugs, ViRexx provides kept protection under the law to many new member nations regarding the european union in addition to selected other countries. Important types contain Portugal, england and the Benelux countries. ViRexx in addition has founded organizing interactions using Dompé Farmaceutici, Medison Pharma, Ltd. in addition to Genesis Pharma Utes. A. for many European in addition to Middle-East Nations around the world.
COPYRIGHT LAWS © 2007 through StockInterview, Inc. JUST ABOUT ALL RIGHTS APPROPRIATED.
Post Source: http: //EzineArticles. com/168741